His manga are known for their unusual visual rhythms and formal devices and for their obsessive and extreme scatological humor.

Enomoto has a cult following in the United States among fans of alternative comics and manga. His works have been enthusiastically reviewed in The Comics Journal, which also published a short untitled comic by him in its Winter 2004 Special Edition. An English language scanlation has been made of The Family Zoo. Works by Enomoto have also been published in Spanish and Italian translations.

Shunji Enomoto is a graduate of Yokohama's Japan Film School.