Hisako Sanada

Reiji's older sister, she is currently around 30 years old, though she is hospitalized in a coma. She was her father's favorite as a child due to her resemblance to her mother. She is 10 when her father is killed and she and her brother are taken in by Doumoto. She has a close friendship with Masatsugu, who she thinks of as a brother. It's implied she's abused by Doumoto though she never reveals this to Reiji. What exactly happened to her is unclear though she may have attempted to take her own life and failed, ending up in a coma.